Coding

Part:BBa_K5185003:Design

Designed by: Zhengyu He   Group: iGEM24_LINKS-China   (2024-10-01)


Human integrins α1 domain（α1）


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 157
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 157
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 157
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 157
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 157
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

We hope to impart antimicrobial properties to wound dressings without the use of antibiotics, so we have chosen defensins. This is because they are of human origin, so there is less likelihood of immune reactions compared to antimicrobial peptides from other species. Defensins also have benefits such as wound healing and inflammation resistance. Additionally, different defensins have varying levels of resistance against different pathogens, so we aim to utilize synthetic biology to produce a variety of materials combined with different defensins in order to offer users more choices.


Source

Homo sapiens

References